In Patient Zero, a global pandemic of a rabies super strain causes the evolution of humanity into a violent new species called "Infected." One human survivor is, somehow, immune, and able to speak the new language of the Infected. He must lead the search for Patient Zero in order to find a cure and save his infected wife and the rest of humankind.
Best known for playing the Eleventh Doctor in Doctor Who, Smith is making the rounds in Hollywood. In addition to Patient Zero, Smith will also play roles in Pride and Prejudice and Zombies and Terminator: Genisys.