I think most Marvel fans would lose their minds if Avengers: Infinity War included a scene in which Thanos was wreaking havoc in New York City and the camera pans away from the cinematic superheroes to show The Defenders, Agents of S.H.I.E.L.D., and the ghost of Peggy Carter pitching in to do their part.
At the moment, any crossover scenario like that remains a pipe dream. Marvel Studios has never confirmed that their small screen superheroes will be included in their cinematic plans, but Marvel producer Nate Moore is offering fans a small sliver of hope.
"I think it's possible for sure," Moore told Slash Film during their Captain America: Civil War set visit. "It's interesting that the TV timeline and the film timeline moves so differently because they tell stories so quickly because they have 10 to 22 episodes. So sometimes it's just hard for those things to line up perfectly. But we love that idea of ultimately, say a Luke Cage, Jessica Jones, Daredevil, Punisher, Agents of SHIELD, maybe there's a way to get 'em back in there as long as it makes sense for our storytelling and doesn't prohibit them from telling a story. We say 'oh, this happened to Daredevil somewhere in the future' and they go 'Well, that's not what the TV show wants us to do.' We don't want that to start to feel like there's friction so we haven't figured out how to do it but we'd love to do it."
Marvel's Avengers: Infinity War Part 1 arrives in theaters May 4, 2018 and Avengers: Infinity War Part 2 will swoop into theaters on May 3, 2019.