The Walking Dead: Three Saviors Who Are Next To Die
Rick Grimes and his band of survivors from Alexandria were on a roll when it came to killing [...]
Simon
Negan's right hand man Simon does not pay enough attention to details as a high ranking Savior should. He is quick to appease his leader but acts quickly, often without thinking too thoroughly.
Furthermore, Simon actor Steven Ogg is a regular on HBO's Westworld series. While he managed to pull of a pair of seasons on both AMC and HBO through The Walking Dead Season 7 and Westworld's premiere season, most actors are not able to manage the conflicting schedules (and sometimes are barred from such efforts, legally).
Simon's death would be a major win for Alexandria, as Negan will realize they're not a threat to be taken lightly, and would throw a wrench into the current ranks among the Saviors.
David
The writing is on the wall (or pages, rather) for David.
With Rosita and Sasha on a mission to the Sanctuary, it's likely at least one of the characters is taken alive to help fuel David's trip towards achieving his comic book destiny.
In the comics, David attempts to rape Abraham's ex-girlfriend Holly but is discovered by Negan in the act. Negan quickly reminds him of the Saviors' "No Rape" policy and stabs him in the neck to make sure he will never attempt such an act again.
David has already been creepy, toying with Enid and her balloons in Alexandria. It's very likely he bows out before Season 7 concludes.
Jared
The one Savior (aside from Negan) who fans really want dead right now is Jared.
Having shot Benjamin and causing Morgan to break his "all life is precious" creed, Jared placed himself atop the target list for Morgan, Carol, the Kingdom, and the fans. Not even Gavin, Jared's leader, is invested in preserving his life after his actions cost Benjamin's.
Jared certainly feels like one of the Saviors who will bow out sooner or later in a moment which will rally the fans, Kingdom, and Alexandria, together.