Take this one with a grain of salt for the time being, since Spoiler TV isn't an official channel, but it seems as though they've found the episode title and plot synopsis for Marvel's Agents of S.H.I.E.L.D.'s second episode--that would be the first one that nobody's seen yet after the pilot screened at San Diego Comic Con International and D23 earlier this year.
Reportedly titled "0-8-4," the plot goes something like this, if true: "Coulson runs into Comandante Camilla Reyes when he and the agents travel to Peru to investigate a mysterious object."
Pretty generic stuff, except that they name-dropped Camilla Reyes, which leads us to suspect that whoever she is, if this synopsis is authentic, she'll be a major player in the first season of the series. There isn't, as far as we know, a Marvel Comics character by that name, but Joss Whedon and company have made it clear that they intend to introduce characters both familiar and entirely new into the Marvel Cinematic Universe via Agents of S.H.I.E.L.D.