Agents Of SHIELD Season 4 Episode 3: May's Health Declines In New Uprising Clip

ABC has released a second clip from Tuesday's "Uprising" episode of Agents of S.H.I.E.L.D.

Coulson and Simmons grow increasingly concerned as they watch, via a remote feed from a CDC facility (located in upper-state New York), Agent May's health decline even further. Her heart rate is erratic; her blood pressure continues to rise, and her adrenaline is spiking.

By the way, the Agents of S.H.I.E.L.D. panel at New York Comic Con took place today, and if you were not in attendance, you can read all about it by clicking here.

As Coulson, Mack and Fitz attempt to track down and neutralize a rogue group looking to end Inhuman Registration worldwide, Simmons and Dr. Radcliffe only have hours to save May before she succumbs forever to her mysterious illness.

The show stars Clark Gregg as Agent Phil Coulson, Ming-Na Wen as Agent Melinda May, Chloe Bennet as Daisy Johnson, Iain De Caestecker as Agent Leo Fitz, Elizabeth Henstridge as Agent Jemma Simmons, and Henry Simmons as Agent Alphonso "Mack" MacKenzie.

The guest-cast includes John Hannah as Holden Radcliffe, Natalia Cordova-Buckley as Elena "Yo-Yo" Rodriguez, Jason O'Mara as the Director, Gabriel Luna as Robbie Reyes, Mallory Jansen as Aida, Parminder Nagra as Senator Rota Nadeer, Alexander Wraith as Agent Anderson, Lorenzo James Henrie as Gabe Reyes, Patrick Cavanaugh as Burrows, Ricky Saenz as pistol punk, Devon Libran as slugger punk, Valery Ortiz as Maria, Derek Hughes as The Amazing Mertz, Preston Flagg as Darryl, Stephanie Maura Sanchez as bridesmaid #1, Jen Kuo Sung as Chen, Dale Pavinski as Briggs, Michael Cory Davis as agitator, Aaron Gaffey as mystery figure, and Adriana Diaz as hostage.

"Uprising" was written by Craig Titley and directed by Magnus Martens.

"Uprising" episode of Marvel's Agents of S.H.I.E.L.D. will air Tuesday, October 11 at 10:00-11:00 p.m. EDT on the ABC Television Network.