5 Best Shows to Binge on Prime Video in September 2025

Prime Video’s streaming options are endless. Amazon’s streaming service features a massive and multi-layered content library that includes some of the best entertainment around, giving subscribers access to thousands of TV shows, movies, and Amazon Originals from the past and present. Every month, the streamer updates its content catalog with a fresh wave of titles, from blockbuster hits to captivating shows. With so many existing streaming options and new titles arriving daily, subscribers can be left endlessly scrolling trying to find that next binge-worthy title. Prime Video’s September 2025 arrivals will make those decisions even more difficult, but we’ve narrowed down the five best TV shows arriving this month.

September 2025 at Prime Video features a few blasts from the past and all-new titles that are sure to be hits. From an award-winning sports drama to a YouTube title that dominated the indie animation world, and even a few new Amazon Originals, these TV shows will have you hooked and immediately pressing play on the next episode. Here are the five best TV shows streaming on Prime Video in September 2025.

5) Helluva Boss

After being a YouTube exclusive, Blitzo and his Hell-based assassination agency known as I.M.P. are heading to Prime Video. Vivienne Medrano’s hit animated series Helluva Boss will join the flagship series Hazbin Hotel on Prime Video on September 10th. The first two complete seasons of Helluva Boss will be available to stream at that time, with Season 3 already ordered.

A leading show in the growing indie adult animation genre, Helluva Boss revolves around Immediate Murder Professionals, or I.M.P., a startup assassination business based in Hell run by the imp Blitzo and his team – weapons specialist Moxxie, bruiser Millie, and receptionist hellhound Loona. The series premiered on YouTube in 2019 as a spin-off of Medrano’s Hazbin Hotel and became an instant hit thanks to its high-quality animation, unique story, and complex and flawed characters. The series also features a strong voice cast that includes Brandon Rogers, Richard Horvitz, Vivian Nixon, Erica Lindbeck, Bryce Pinkham, and Alex Brightman.

4) The Girlfriend

If you’re looking for a tense new psychological thriller to keep you on the edge of your seat, look no further than The Girlfriend. Prime Video’s anticipated adaptation of Michelle Frances’ novel of the same name, starring Laurie Davidson, Olivia Cooke, and Robin Wright, is scheduled to debut on Prime Video on September 10th.

The Girlfriend is a gripping family drama that centers around Laura, a woman who seemingly has it all. But her picture-perfect life begins to crumble when her son Daniel brings home a new girlfriend named Cherry. Laura becomes convinced that Cherry is hiding something. The show focuses on the escalating competition between Laura and Cherry for Daniel’s attention and will leave viewers wondering if Laura is just paranoid or if Cherry is actually a manipulative social climber.

3) Gen V

Prime Video is re-enrolling at Godolkin University. The streamer’s college-set The Boys spin-off Gen V returns for its second season on September 17th, and Season 1 is available to stream in full. Created by Craig Rosenberg, Evan Goldberg, and Eric Kripke and based on The Boys comic book story arc We Gotta Go Now, the satirical superhero series is set at America’s only college for superheroes. The show follows a group of young supes as they put their physical, sexual, and moral boundaries to the test. In Season 2, America continues to adjust to Homelander’s reign, and a mysterious new Dean preaches a curriculum that promises to make students more powerful than ever.

Gen V is a perfect expansion of The Boys universe that brings the dark, satirical elements of the flagship show together with a traditional coming-of-age story, offering a new take on superhero origins that is filled with adolescent angst. The show stars Jaz Sinclair, Chance Perdomo, Lizze Broadway, Maddie Phillips, London Thor, Derek Luh, Asa Germann, and Shelley Conn as the young supes, all complex characters trying to find their paths in the complicated world.

2) The Good Place

The Good Place is leaving Netflix in September, but fans won’t have to be in The Bad Place for long. The hit NBC sitcom will move to Prime Video beginning September 26th, with all four seasons and 56 episodes available to stream at that time. Created by Michael Schur, the series stars Kristen Bell as Eleanor Shellstrop, a corrupt saleswoman who finds herself in the afterlife, surprised that she has made it to The Good Place. Determined to stay, she tries to shed her old way of life and become a better person. Ted Danson, William Jackson Harper, Jameela Jamil, Manny Jacinto, and D’Arcy Carden star.

The Good Place aired on NBC from 2016 until 2020 and quickly established itself as one of the best sitcoms ever. The series perfectly balances its deep exploration of philosophical ideas with the typical sitcom humor, heartwarming moments, and plot twists and received high praise for its strong writing, great cast, and originality.

1) Friday Night Lights

“Clear eyes, full hearts, can’t lose,” because Friday Night Lights is on Prime Video. All five seasons of Peter Berg’s beloved sports drama series started streaming on Amazon’s streaming service on September 1st. Inspired by H. G. Bissinger’s 1990 non-fiction novel Friday Night Lights: A Town, a Team, and a Dream, the series paints a realistic portrayal of small-town life in Middle America. The show is set in the rural town of Dillon, Texas, where high school football is the community’s way of life. The show explores the lives of the Panthers, a high school football team, and their coach on and off the field and the issues facing small-town America.

Friday Night Lights ran for five seasons and 76 episodes on NBC from 2006 to 2011, its compelling character-driven stories and relatability making it an instant classic. The stellar cast featured Kyle Chandler, Connie Britton, Gaius Charles, Zach Gilford, Minka Kelly, Adrianne Palicki, Taylor Kitsch, Jesse Plemons, Scott Porter, Aimee Teegarden, Michael B. Jordan, Jurnee Smollett, Matt Lauria, Madison Burge, and Grey Damon.

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